Bacteria Isolated and Their Antimicrobial Resistance in A Pediatric Intensive Care Unit

Abstract

Background:

The AMR conditions between several bacterial genera have been a significant issue in pediatric intensive care units (PICUs), especially due to the deleterious effects it has, such as increased morbidity and mortality of patients as well as complicating their treatment which is already a very difficult task. Thus, it becomes a dire necessity to be able to manage and control these infections by understanding the bacterial profiles and their resistance towards certain isolates.

Objective:

Our objective was to determine the bacterial profiles in patients located in the PICU, and also the bacterial resistance against antimicrobial compounds, so that further measures for infection control and evaluation can be taken.

Methodology:

A Total of six months was taken for cross sectional observation of this case in a tertiary care unit located in a PICU. Blood, urine and respiratory samples of the pediatric patients suffering from infectious diseases were collected. The Samples collected were then subjected to routine microbiology and antibiotic sensitivity tests. Following that test, the data collected was analyzed so that the behaviour of the strains in response to the antibiotics can be predicted.

Results:

Over 150 bacterial strains were identified as common pathogens which included Klebsiella pneumoniae (25%), staphylococcus aureus and Acinetobacter baumannii (20%, 15% respectively). There is a clear increase in antibiotic resistance observed in this test, ranging from 70% of k la pneumoniae to 60% of Mudacineters. Methicillin-resistant staphylococcus aureus has been the invading organism with a 30% prevalence in a Staphylococcus aureus preserve. Multidrug resistant organisms made up about 40% of the isolates.

Conclusion:

This research depicts clearly the high level of antimicrobial resistance that exists in bacterial isolates as gathered in a PICU which has ramifications on treatment plans and strategies that may be used to control the infections. Surveillance and fight against AMR in the pediatric population can be achieved through the strong need for continuous surveillances and use of antimicrobial medications.