Factors Contributing to Mortality in Hospitalized Heart Failure Patients

Authors

  • Dr. Fuad Abdullah Dhaidan M.B.Ch.B, D.M, CABM. Specialist in physician, department of internal medicine.

Keywords:

Heart failure, mortality, hospitalization, associated factors

Abstract

Background: Heart Failure (HF) is a persistent and progressive cardiac condition that hinders the heart's ability to adequately circulate blood, resulting in insufficient supply of oxygen and nutrients to other organs. The condition can occur at any age, however the likelihood of experiencing it rises with age. Objective: to assess the factors contributing to mortality in hospitalized heart failure patients.

Patients and methods: Data base study which is included all hospitalized patients recorded with primary diagnosis of heart failure (HF) in our hospitals in Baghdad city for 2 years duration in the period from 2020-2022, with in the age 20 years and over.

Results: The main age group was in between 50-60 years (25.1%), and female (53.7%) were more than male (46.3%) with female to male ratio = 1.16:1. Arrhythmia were found in 53.7% of the patients, while long QTc were presented in 38.8% of them. 63 (24.7%) were dead and female represented in (61%) while male was represented (39%), Patients diagnosed with heart failure and subsequently admitted with problems had a 5.13-fold increased likelihood of mortality compared to those without difficulties. Patients who do not have cardiogenic shock had a 98.7% lower probability of death related to patients complicated by cardiogenic shock. Those who presented with an ejection fraction ranging from 30%–50% had an 89% lower likelihood of mortality associated to patients with an ejection percentage of ≤30.

Conclusion: prevalence of HF in female were more than male, and the female sex alone does not constitute a factor associated with higher in-hospital lethality, but the observed excess risk is related to at his oldest age.

 

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References

Aranha LN. TG/HDL-c Ratio as a Predictor of Cardiovascular Risk. International Journal of Cardiovascular Sciences. 2021 Nov 1;34:66-7.

Savarese G, Becher PM, Lund LH, Seferovic P, Rosano GM, Coats AJ. Global burden of heart failure: a comprehensive and updated review of epidemiology. Cardiovascular research. 2022 Dec 1;118(17):3272-87.

Lippi G, Sanchis-Gomar F. Global epidemiology and future trends of heart failure. AME medical journal. 2020 Jun 25;5.

Huang W, Lee SG, How CH. Management of the heart failure patient in the primary care setting. Singapore Medical Journal. 2020 May;61(5):225.

Oh JK. Echocardiography in heart failure: beyond diagnosis. European Journal of Echocardiography. 2007 Jan 1;8(1):4-14.

Maries L, Manitiu I. Diagnostic and prognostic values of B-type natriuretic peptides (BNP) and N-terminal fragment brain natriuretic peptides (NT-pro-BNP). Cardiovascular journal of Africa. 2013 Aug 1;24(7):286-9.

McCullough PA, Neyou A. Comprehensive review of the relative clinical utility of B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide assays in cardiovascular disease. Open Heart Failure Journal. 2009 Jun 11;2(1).

Blair JE, Huffman M, Shah SJ. Heart failure in north america. Current cardiology reviews. 2013 May 1;9(2):128-46.

AlHabib KF, Elasfar AA, AlBackr H, et al. Design and preliminary results of the Heart Function Assessment Registry Trial in Saudi Arabia (HEARTS) in patients with acute and chronic heart failure. Eur J Heart Fail. 2011;13:1178–84.

Agarwal AK, Venugopalan P, de Bono D. Prevalence and aetiology of heart failure in an Arab population. Eur J Heart Failure. 2001;3:301–5.

Arrigo M, Jessup M, Mullens W, Reza N, Shah AM, Sliwa K, Mebazaa A. Acute heart failure. Nature Reviews Disease Primers. 2020 Mar 5;6(1):16.

Agbor VN, Essouma M, Ntusi NA, Nyaga UF, Bigna JJ, Noubiap JJ. Heart failure in sub-Saharan Africa: a contemporaneous systematic review and meta-analysis. International journal of cardiology. 2018 Apr 15;257:207-15.

Diaz-Toro F, Nazzal NC, Verdejo PH. Incidence and hospital mortality due to heart failure. Are there any differences by sex?. Revista Medica de Chile. 2017 Jun 1;145(6):703-9.

Stock EO, Redberg R. Cardiovascular disease in women. Current problems in cardiology. 2012 Nov 1;37(11):450-526.

LaMarca B, Alexander BT, editors. Sex differences in cardiovascular physiology and pathophysiology. Academic Press; 2019 Apr 9.

Lonardo A, Suzuki A. Sexual dimorphism of NAFLD in adults. Focus on clinical aspects and implications for practice and translational research. Journal of clinical medicine. 2020 Apr 28;9(5):1278.

Ho KK, Pinsky JL, Kannel WB, Levy D. The epidemiology of heart failure: the Framingham Study. J Am Coll Cardiol 1993; 22 (4 Suppl A): 6A-13A.

Bui AL, Horwich TB, Fonarow GC. Epidemiology and risk profile of heart failure. Nature Reviews Cardiology. 2011 Jan;8(1):30-41.

Mehta PA, Cowie MR. Gender and heart failure: a population perspective. Heart 2006; 92 Suppl 3: iii14-8.

Tadic M, Cuspidi C, Plein S, Belyavskiy E, Heinzel F, Galderisi M. Sex and heart failure with preserved ejection fraction: from pathophysiology to clinical studies. Journal of clinical medicine. 2019 Jun 4;8(6):792.

Maas AH, Appelman YE. Gender differences in coronary heart disease. Neth Heart J 2010; 18 (12): 598-602.

Mendoza W, Miranda JJ. Global shifts in cardiovascular disease, the epidemiologic transition, and other contributing factors: toward a new practice of global health cardiology. Cardiology clinics. 2017 Feb 1;35(1):1-2.

Fonseca C, Sarmento PM, Marques F, Ceia F. Validity of a discharge diagnosis of heart failure: implications of misdiagnosing. Congest Heart Fail 2008; 14 (4): 187-91.

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Published

2023-12-18

How to Cite

Dhaidan, D. F. A. (2023). Factors Contributing to Mortality in Hospitalized Heart Failure Patients. Academic Journal of Clinicians, 5(03), 72–80. Retrieved from https://clinician.site/index.php/ajcs/article/view/29