Analysis of Microbiological Results and Sensitivity to Antimicrobial Agents in Emergency Abdominal Surgery
Keywords:
intra-abdominal infection; antibiotics; cultures.Abstract
Background: It is crucial to uphold bacterial surveillance programs in order to decrease resistance and establish suitable pharmaceutical strategies. Patients with acute abdomen have a distinct microbiological subgroup.
Objectives: To conduct a comprehensive assessment of harmful microorganisms in adult patients who underwent emergency surgery for abdominal conditions with the presence of fluid, and to analyse the findings of bacterial cultures in terms of strains and their resistance to antibiotics. Materials and Method: Conducting a study on a group of individuals to gather information about their characteristics and using statistical methods to summarise and describe the data. This study includes consecutive patients who are over 18 years of age and underwent surgery for acute abdomen with the presence of intraperitoneal free fluid. The study period spans from October 2022 to July 1, 2023. Patients who have had antimicrobial therapy, been hospitalized, or undergone surgery in the past 3 months are not included in the study. The study includes analysis of positive cultures, identification of specific strains, assessment of susceptibility to antimicrobial agents, collection of demographic data, and evaluation of clinical progression.
Results: Out of a total of 63 patients, 55% were male, with an average age of 52.2 years. The most common pathologies were of appendicular origin (62%) and of intestinal origins (30%). The cultivation showed a favorable growth rate of 44%, with 36% of cases exhibiting multiple germs. Escherichia coli was the predominant pathogen, accounting for 64.2% of cases, followed by Enterococcus faecium and Streptococcus anginosus at 7.1% each. Among the other farmed infections, multiple resistance was only observed in a single isolated case of Morganella Morganii.
Conclusions: This data represents the specific microbiological situation in cases of acute abdomen in the local area. Escherichia coli is the most prevalent pathogen that necessitates prophylaxis and proper antibiotic therapy. Local microbiological surveillance must be maintained to ensure proper management.
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